Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia

With the use of risk-directed therapy for childhood acute lymphoblastic leukemia (ALL), outcome has improved dramatically in the past 40 years. However, a substantial portion of patients, many of whom have no known risk factors, experience relapse. Taking a genome-wide approach, in the present study...

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Detalhes bibliográficos
Main Authors: Yang, Jun J., Cheng, Cheng, Devidas, Meenakshi, Cao, Xueyuan, Campana, Dario, Yang, Wenjian, Fan, Yiping, Neale, Geoff, Cox, Nancy, Scheet, Paul, Borowitz, Michael J., Winick, Naomi J., Martin, Paul L., Bowman, W. Paul, Camitta, Bruce, Reaman, Gregory H., Carroll, William L., Willman, Cheryl L., Hunger, Stephen P., Evans, William E., Pui, Ching-Hon, Loh, Mignon, Relling, Mary V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501717/
https://ncbi.nlm.nih.gov/pubmed/23007406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-440107
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