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Profiling Impaired Hepatic Endoplasmic Reticulum Glycosylation as a Consequence of Ethanol Ingestion

Alcoholic liver disease (ALD) is a prominent cause of morbidity and mortality in the United States. Alterations in protein folding occur in numerous disease states, including ALD. The endoplasmic reticulum (ER) is the primary site of post-translational modifications (PTM) within the cell. Glycosylat...

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Main Authors: Galligan, James J., Fritz, Kristofer S., Tipney, Hannah, Smathers, Rebecca L., Roede, James R., Shearn, Colin T., Hunter, Lawrence E., Petersen, Dennis R.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501204/
https://ncbi.nlm.nih.gov/pubmed/21319786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr101101s
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