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Profiling Impaired Hepatic Endoplasmic Reticulum Glycosylation as a Consequence of Ethanol Ingestion

Alcoholic liver disease (ALD) is a prominent cause of morbidity and mortality in the United States. Alterations in protein folding occur in numerous disease states, including ALD. The endoplasmic reticulum (ER) is the primary site of post-translational modifications (PTM) within the cell. Glycosylat...

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Detalhes bibliográficos
Main Authors: Galligan, James J., Fritz, Kristofer S., Tipney, Hannah, Smathers, Rebecca L., Roede, James R., Shearn, Colin T., Hunter, Lawrence E., Petersen, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501204/
https://ncbi.nlm.nih.gov/pubmed/21319786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr101101s
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