Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

BRCA1, a well-known tumor suppressor with multiple interacting partners, is predicted to have diverse biological functions. However, so far its only well-established role is in the repair of damaged DNA and cell cycle regulation. In this regard, the etiopathological study of low-penetrant variants o...

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Hlavní autoři: Chang, Suhwan, Wang, Rui-Hong, Akagi, Keiko, Kim, Kyung-Ae, Martin, Betty K, Cavallone, Luca, Haines, Diana C, Basik, Mark, Mai, Phuong, Poggi, Elizabeth, Isaacs, Claudine, Looi, Lai M, Mun, Kein S, Greene, Mark H, Byers, Stephen W, Teo, Soo H, Deng, Chu-Xia, Sharan, Shyam K
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501198/
https://ncbi.nlm.nih.gov/pubmed/21946536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2459
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