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The role of epigenetic transcriptional regulation in BRCA1-mediated tumor suppression
Mutation in BRCA1 accounts for half of all familial breast cancer cases. Recent studies have shown its role in the epigenetic regulation of an oncogenic microRNA, revealing a novel mode of tumor suppression that is independent of its well-established role in DNA repair and cell cycle regulation.
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644038/ https://ncbi.nlm.nih.gov/pubmed/23131665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.22600 |
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