Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

BRCA1, a well-known tumor suppressor with multiple interacting partners, is predicted to have diverse biological functions. However, so far its only well-established role is in the repair of damaged DNA and cell cycle regulation. In this regard, the etiopathological study of low-penetrant variants o...

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Autores principales: Chang, Suhwan, Wang, Rui-Hong, Akagi, Keiko, Kim, Kyung-Ae, Martin, Betty K, Cavallone, Luca, Haines, Diana C, Basik, Mark, Mai, Phuong, Poggi, Elizabeth, Isaacs, Claudine, Looi, Lai M, Mun, Kein S, Greene, Mark H, Byers, Stephen W, Teo, Soo H, Deng, Chu-Xia, Sharan, Shyam K
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501198/
https://ncbi.nlm.nih.gov/pubmed/21946536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2459
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