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Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

BRCA1, a well-known tumor suppressor with multiple interacting partners, is predicted to have diverse biological functions. However, so far its only well-established role is in the repair of damaged DNA and cell cycle regulation. In this regard, the etiopathological study of low-penetrant variants o...

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Bibliografiske detaljer
Main Authors: Chang, Suhwan, Wang, Rui-Hong, Akagi, Keiko, Kim, Kyung-Ae, Martin, Betty K, Cavallone, Luca, Haines, Diana C, Basik, Mark, Mai, Phuong, Poggi, Elizabeth, Isaacs, Claudine, Looi, Lai M, Mun, Kein S, Greene, Mark H, Byers, Stephen W, Teo, Soo H, Deng, Chu-Xia, Sharan, Shyam K
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501198/
https://ncbi.nlm.nih.gov/pubmed/21946536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2459
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