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Regulatory Subunit Myristoylation Antagonizes Calcineurin Phosphatase Activation in Yeast

The Ca(2+)/calmodulin-stimulated protein phosphatase calcineurin is a critical component of Ca(2+) signaling cascades in eukaryotic cells. Myristoylation of the regulatory subunit of calcineurin (CNB) is conserved from yeast to humans. Here, we show that CNB myristoylation antagonizes phosphatase ac...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Connolly, Sean, Kingsbury, Tami
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501033/
https://ncbi.nlm.nih.gov/pubmed/23027860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.366617
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