Calcineurin Regulatory Subunit Calcium-Binding Domains Differentially Contribute to Calcineurin Signaling in Saccharomyces cerevisiae

The protein phosphatase calcineurin is central to Ca(2+) signaling pathways from yeast to humans. Full activation of calcineurin requires Ca(2+) binding to the regulatory subunit CNB, comprised of four Ca(2+)-binding EF hand domains, and recruitment of Ca(2+)-calmodulin. Here we report the consequen...

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Bibliographic Details
Published in:Genetics
Main Authors: Connolly, Sean, Quasi-Woode, Devona, Waldron, Laura, Eberly, Christian, Waters, Kerri, Muller, Eric M., Kingsbury, Tami J.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2018
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028253/
https://ncbi.nlm.nih.gov/pubmed/29735720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300911
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