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Regulatory Subunit Myristoylation Antagonizes Calcineurin Phosphatase Activation in Yeast

The Ca(2+)/calmodulin-stimulated protein phosphatase calcineurin is a critical component of Ca(2+) signaling cascades in eukaryotic cells. Myristoylation of the regulatory subunit of calcineurin (CNB) is conserved from yeast to humans. Here, we show that CNB myristoylation antagonizes phosphatase ac...

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Detalhes bibliográficos
Main Authors: Connolly, Sean, Kingsbury, Tami
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501033/
https://ncbi.nlm.nih.gov/pubmed/23027860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.366617
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