Functional Equilibrium of the KcsA Structure Revealed by NMR

KcsA is a tetrameric K(+) channel that is activated by acidic pH. Under open conditions of the helix bundle crossing, the selectivity filter undergoes an equilibrium between permeable and impermeable conformations. Here we report that the population of the permeable conformation (p(perm)) positively...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Imai, Shunsuke, Osawa, Masanori, Mita, Kenichiro, Toyonaga, Shou, Machiyama, Asako, Ueda, Takumi, Takeuchi, Koh, Oiki, Shigetoshi, Shimada, Ichio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501015/
https://ncbi.nlm.nih.gov/pubmed/23024361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.401265
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