Specificity of Linear Motifs That Bind to a Common Mitogen-Activated Protein Kinase Docking Groove

Mitogen activated protein kinases (MAPKs) have a docking groove that interacts with linear motifs in binding partners. To determine the structural basis of binding specificity between MAPKs and docking motifs, we quantitatively analyzed the ability of fifteen linear motifs from diverse MAPK partners...

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Détails bibliographiques
Auteurs principaux: Garai, Ágnes, Zeke, András, Gógl, Gergö, Törö, Imre, Ferenc, Fördös, Blankenburg, Hagen, Bárkai, Tünde, Varga, János, Alexa, Anita, Emig, Dorothea, Albrecht, Mario, Reményi, Attila
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500698/
https://ncbi.nlm.nih.gov/pubmed/23047924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003004
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