Specificity of Linear Motifs That Bind to a Common Mitogen-Activated Protein Kinase Docking Groove

Mitogen activated protein kinases (MAPKs) have a docking groove that interacts with linear motifs in binding partners. To determine the structural basis of binding specificity between MAPKs and docking motifs, we quantitatively analyzed the ability of fifteen linear motifs from diverse MAPK partners...

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Autores principales: Garai, Ágnes, Zeke, András, Gógl, Gergö, Törö, Imre, Ferenc, Fördös, Blankenburg, Hagen, Bárkai, Tünde, Varga, János, Alexa, Anita, Emig, Dorothea, Albrecht, Mario, Reményi, Attila
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500698/
https://ncbi.nlm.nih.gov/pubmed/23047924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003004
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