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Biosynthesis of Athmu, a α,γ-hydroxy-β-amino acid of pahayokolides A–B

Pahayokolides A–B are cyanobacteria derived non-ribosomal peptides which exhibit cytotoxicity against a number of cancer cell lines. The biosynthetic origin of the 3-amino-2,5,7,8-tetrahydroxy-10-methylundecanoic acid (Athmu) moiety has been investigated using stable isotope incorporation experiment...

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Detalhes bibliográficos
Main Authors: Liu, Li, Bearden, Daniel W., Rodriguez, Juan C., Rein, Kathleen S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500633/
https://ncbi.nlm.nih.gov/pubmed/23172981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.09.119
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