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RAPADILINO RECQL4 Mutant Protein Lacks Helicase and ATPase Activity

The RecQ family of helicases has been shown to play an important role in maintaining genomic stability. In humans, this family has five members and mutations in three of these helicases, BLM, WRN and RECQL4, are associated with disease. Alterations in RECQL4 are associated with three diseases, Rothm...

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Detalhes bibliográficos
Main Authors: Croteau, Deborah L., Rossi, Marie L., Ross, Jennifer, Dawut, Lale, Dunn, Christopher, Kulikowicz, Tomasz, Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500628/
https://ncbi.nlm.nih.gov/pubmed/22885111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.07.014
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