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RAPADILINO RECQL4 Mutant Protein Lacks Helicase and ATPase Activity
The RecQ family of helicases has been shown to play an important role in maintaining genomic stability. In humans, this family has five members and mutations in three of these helicases, BLM, WRN and RECQL4, are associated with disease. Alterations in RECQL4 are associated with three diseases, Rothm...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3500628/ https://ncbi.nlm.nih.gov/pubmed/22885111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.07.014 |
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