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Probing a 2-Aminobenzimidazole Library for Binding to RNA Internal Loops via Two-Dimensional Combinatorial Screening

There are many potential RNA drug targets in bacterial, viral, and the human transcriptomes. However, there are few small molecules that modulate RNA function. This is due, in part, to a lack of fundamental understanding about RNA-ligand interactions including the types of small molecules that bind...

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Detaylı Bibliyografya
Asıl Yazarlar: Velegapudi, Sai Pradeep, Pushechnikov, Alexei, Labuda, Lucas P., French, Jonathan M., Disney, Matthew D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500435/
https://ncbi.nlm.nih.gov/pubmed/22958065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300213g
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