Lymphatic Reprogramming by Kaposi Sarcoma Herpes Virus Promotes the Oncogenic Activity of the Virus-Encoded G-protein Coupled Receptor

Kaposi sarcoma (KS), the most common cancer in HIV-positive individuals, is caused by endothelial transformation mediated by the KS herpes virus (KSHV)-encoded G-protein coupled receptor (vGPCR). Infection of blood vascular endothelial cells (BECs) by KSHV reactivates an otherwise silenced embryonic...

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Autori principali: Aguilar, Berenice, Choi, Inho, Choi, Dongwon, Chung, Hee Kyoung, Lee, Sunju, Yoo, Jaehyuk, Lee, Yong Suk, Maeng, Yong Sun, Lee, Ha Neul, Park, Eunkyung, Kim, Kyu Eui, Kim, Nam Yoon, Baik, Jae Myung, Jung, Jae U., Koh, Chester J., Hong, Young-Kwon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500425/
https://ncbi.nlm.nih.gov/pubmed/22942256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1229
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