Lymphatic Reprogramming by Kaposi Sarcoma Herpes Virus Promotes the Oncogenic Activity of the Virus-Encoded G-protein Coupled Receptor

Kaposi sarcoma (KS), the most common cancer in HIV-positive individuals, is caused by endothelial transformation mediated by the KS herpes virus (KSHV)-encoded G-protein coupled receptor (vGPCR). Infection of blood vascular endothelial cells (BECs) by KSHV reactivates an otherwise silenced embryonic...

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Hoofdauteurs: Aguilar, Berenice, Choi, Inho, Choi, Dongwon, Chung, Hee Kyoung, Lee, Sunju, Yoo, Jaehyuk, Lee, Yong Suk, Maeng, Yong Sun, Lee, Ha Neul, Park, Eunkyung, Kim, Kyu Eui, Kim, Nam Yoon, Baik, Jae Myung, Jung, Jae U., Koh, Chester J., Hong, Young-Kwon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500425/
https://ncbi.nlm.nih.gov/pubmed/22942256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1229
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