Lymphatic Reprogramming by Kaposi Sarcoma Herpes Virus Promotes the Oncogenic Activity of the Virus-Encoded G-protein Coupled Receptor

Kaposi sarcoma (KS), the most common cancer in HIV-positive individuals, is caused by endothelial transformation mediated by the KS herpes virus (KSHV)-encoded G-protein coupled receptor (vGPCR). Infection of blood vascular endothelial cells (BECs) by KSHV reactivates an otherwise silenced embryonic...

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Main Authors: Aguilar, Berenice, Choi, Inho, Choi, Dongwon, Chung, Hee Kyoung, Lee, Sunju, Yoo, Jaehyuk, Lee, Yong Suk, Maeng, Yong Sun, Lee, Ha Neul, Park, Eunkyung, Kim, Kyu Eui, Kim, Nam Yoon, Baik, Jae Myung, Jung, Jae U., Koh, Chester J., Hong, Young-Kwon
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500425/
https://ncbi.nlm.nih.gov/pubmed/22942256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1229
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