The Lymphatic Cell Environment Promotes Kaposi Sarcoma Development by Prox1-Enhanced Productive Lytic Replication of Kaposi Sarcoma Herpes Virus

Kaposi’s sarcoma (KS) is the most common cancer in HIV-positive individuals and is caused by KS-associated herpesvirus (KSHV). It is believed that a small number of latently infected KS tumor cells undergo spontaneous lytic reactivation to produce viral progeny for infection of new cells. Here we us...

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Pubblicato in:Cancer Res
Autori principali: Choi, Dongwon, Park, Eunkyung, Kim, Kyu Eui, Jung, Eunson, Seong, Young Jin, Zhao, Luping, Madhavan, Shrimika, Daghlian, George, Lee, Hansuh H., Daghlian, Patill T., Daghlian, Saren, Bui, Khoa, Koh, Chester J., Wong, Alex K., Cho, Il-Taeg, Hong, Young-Kwon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759148/
https://ncbi.nlm.nih.gov/pubmed/32518204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3105
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