The Lymphatic Cell Environment Promotes Kaposi Sarcoma Development by Prox1-Enhanced Productive Lytic Replication of Kaposi Sarcoma Herpes Virus

Kaposi’s sarcoma (KS) is the most common cancer in HIV-positive individuals and is caused by KS-associated herpesvirus (KSHV). It is believed that a small number of latently infected KS tumor cells undergo spontaneous lytic reactivation to produce viral progeny for infection of new cells. Here we us...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Choi, Dongwon, Park, Eunkyung, Kim, Kyu Eui, Jung, Eunson, Seong, Young Jin, Zhao, Luping, Madhavan, Shrimika, Daghlian, George, Lee, Hansuh H., Daghlian, Patill T., Daghlian, Saren, Bui, Khoa, Koh, Chester J., Wong, Alex K., Cho, Il-Taeg, Hong, Young-Kwon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759148/
https://ncbi.nlm.nih.gov/pubmed/32518204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3105
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