تحميل...

Bicyclic core estrogens as full antagonists: synthesis, biological evaluation and structure–activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfonamides()

Compounds that block estrogen action through the estrogen receptor (ER) or downregulate ER levels are useful for the treatment of breast cancer and endocrine disorders. In our search for structurally novel estrogens having three-dimensional core scaffolds, we found some compounds with a 7-oxabicyclo...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zhu, Manghong, Zhang, Chen, Nwachukwu, Jerome C., Srinivasan, Sathish, Cavett, Valerie, Zheng, Yangfan, Carlson, Kathryn E., Dong, Chune, Katzenellenbogen, John A., Nettles, Kendall W., Zhou, Hai-Bing
التنسيق: Artigo
اللغة:Inglês
منشور في: 2012
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500388/
https://ncbi.nlm.nih.gov/pubmed/23033157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ob26531a
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