Analysis of the Native Structure, Stability and Aggregation of Biotinylated Human Lysozyme

Fibril formation by mutational variants of human lysozyme is associated with a fatal form of hereditary non-neuropathic systemic amyloidosis. Defining the mechanistic details of lysozyme aggregation is of crucial importance for understanding the origin and progression of this disease and related mis...

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Bibliografiske detaljer
Main Authors: Ahn, Minkoo, De Genst, Erwin, Kaminski Schierle, Gabriele S., Erdelyi, Miklos, Kaminski, Clemens F., Dobson, Christopher M., Kumita, Janet R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500338/
https://ncbi.nlm.nih.gov/pubmed/23166837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050192
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