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Analysis of the Native Structure, Stability and Aggregation of Biotinylated Human Lysozyme

Fibril formation by mutational variants of human lysozyme is associated with a fatal form of hereditary non-neuropathic systemic amyloidosis. Defining the mechanistic details of lysozyme aggregation is of crucial importance for understanding the origin and progression of this disease and related mis...

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Detalhes bibliográficos
Main Authors: Ahn, Minkoo, De Genst, Erwin, Kaminski Schierle, Gabriele S., Erdelyi, Miklos, Kaminski, Clemens F., Dobson, Christopher M., Kumita, Janet R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500338/
https://ncbi.nlm.nih.gov/pubmed/23166837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050192
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