Yüklüyor......
Epigenetic Modification of the Repair Donor Regulates Targeted Gene Correction
Optimizing design of vectors is critical to effective gene therapy. In targeted gene correction (TGC), cleavage of chromosomal DNA near a mutation stimulates homology-directed repair of a target gene using a donor provided in trans. We have systematically addressed epigenetic parameters of donor des...
Kaydedildi:
| Asıl Yazarlar: | , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2012
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499697/ https://ncbi.nlm.nih.gov/pubmed/23344649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.42 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|