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Epigenetic Modifications as Therapeutic Targets

Epigenetic modifications work with genetic mechanisms to determine transcriptional activity and, while somatically heritable they are also reversible, making them good therapeutic candidates. Epigenetic changes can precede disease pathology and thus are diagnostic indicators for risk, and can act as...

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Detalles Bibliográficos
Main Authors: Kelly, Theresa K, De Carvalho, Daniel D, Jones, Peter A
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022972/
https://ncbi.nlm.nih.gov/pubmed/20944599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1678
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