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Epigenetic Modifications as Therapeutic Targets

Epigenetic modifications work with genetic mechanisms to determine transcriptional activity and, while somatically heritable they are also reversible, making them good therapeutic candidates. Epigenetic changes can precede disease pathology and thus are diagnostic indicators for risk, and can act as...

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Autores principales: Kelly, Theresa K, De Carvalho, Daniel D, Jones, Peter A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022972/
https://ncbi.nlm.nih.gov/pubmed/20944599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1678
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