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Sarcomas in hereditary retinoblastoma

Children diagnosed with the hereditary form of retinoblastoma (Rb), a rare eye cancer caused by a germline mutation in the RB1 tumor suppressor gene, have excellent survival, but face an increased risk of bone and soft tissue sarcomas. This predisposition to sarcomas has been attributed to genetic s...

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Bibliografiske detaljer
Main Authors: Kleinerman, Ruth A, Schonfeld, Sara J, Tucker, Margaret A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499233/
https://ncbi.nlm.nih.gov/pubmed/23036192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-2-15
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