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Sarcomas in hereditary retinoblastoma

Children diagnosed with the hereditary form of retinoblastoma (Rb), a rare eye cancer caused by a germline mutation in the RB1 tumor suppressor gene, have excellent survival, but face an increased risk of bone and soft tissue sarcomas. This predisposition to sarcomas has been attributed to genetic s...

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Detalhes bibliográficos
Main Authors: Kleinerman, Ruth A, Schonfeld, Sara J, Tucker, Margaret A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499233/
https://ncbi.nlm.nih.gov/pubmed/23036192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-2-15
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