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Sarcomas in hereditary retinoblastoma

Children diagnosed with the hereditary form of retinoblastoma (Rb), a rare eye cancer caused by a germline mutation in the RB1 tumor suppressor gene, have excellent survival, but face an increased risk of bone and soft tissue sarcomas. This predisposition to sarcomas has been attributed to genetic s...

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Autors principals: Kleinerman, Ruth A, Schonfeld, Sara J, Tucker, Margaret A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499233/
https://ncbi.nlm.nih.gov/pubmed/23036192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-2-15
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