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Protection from feed-forward amplification in an amplified RNAi mechanism
The effectiveness of RNA interference (RNAi) in many organisms is potentiated through the signal-amplifying activity of a targeted RNA directed RNA polymerase (RdRP) system that can convert a small population of exogenously-encountered dsRNA fragments into an abundant internal pool of small interfer...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499135/ https://ncbi.nlm.nih.gov/pubmed/23141544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.10.022 |
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