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Distinct phases of siRNA synthesis in an endogenous RNAi pathway in C. elegans soma
Endogenous RNA-directed RNA polymerases (RdRPs) are cellular components capable of synthesizing new complementary RNAs from existing RNA templates. We present evidence for successive engagement of two different RdRPs in an endogenous siRNA-based mechanism targeting specific mRNAs in C. elegans soma....
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838994/ https://ncbi.nlm.nih.gov/pubmed/20116306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.01.012 |
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