Structural insights into the specific anti-HIV property of actinohivin: structure of its complex with the α(1–2)mannobiose moiety of gp120

Actinohivin (AH) is an actinomycete lectin with a potent specific anti-HIV activity. In order to clarify the structural evidence for its specific binding to the α(1–2)mannobiose (MB) moiety of the D1 chains of high-mannose-type glycans (HMTGs) attached to HIV-1 gp120, the crystal structure of AH in...

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Detalhes bibliográficos
Main Authors: Hoque, M. Mominul, Suzuki, Kaoru, Tsunoda, Masaru, Jiang, Jiandong, Zhang, Fang, Takahashi, Atsushi, Ohbayashi, Naomi, Zhang, Xiaoxue, Tanaka, Haruo, Ōmura, Satoshi, Takénaka, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498932/
https://ncbi.nlm.nih.gov/pubmed/23151632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444912040498
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