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Crystallographic study of the interaction of the anti-HIV lectin actinohivin with the α(1–2)mannobiose moiety of gp120 HMTG

Actinohivin (AH) is a new potent anti-HIV lectin of microbial origin. In order to modify it to produce a more efficient drug, its three-dimensional structure has previously been determined with and without the target α(1–2)mannobiose moiety of the high-mannose-type glycan (HMTG) attached to HIV-1 gp...

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Detalhes bibliográficos
Main Authors: Suzuki, Kaoru, Ohbayashi, Naomi, Jiang, Jiandong, Zhang, Xiaoxue, Hoque, M. Mominul, Tsunoda, Masaru, Murayama, Kazutaka, Tanaka, Haruo, Takénaka, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433197/
https://ncbi.nlm.nih.gov/pubmed/22949194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112031077
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