Structural insights into the catalytic reaction trigger and inhibition of d-3-hydroxybutyrate dehydrogenase

d-3-Hydroxybutyrate dehydrogenase catalyzes the reversible conversion of acetoacetate and d-3-hydroxybutyrate. These ketone bodies are both energy-storage forms of acetyl-CoA. In order to clarify the structural mechanisms of the catalytic reaction with the cognate substrate d-3-hydroxybutyrate and o...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Kanazawa, Hiroki, Hoque, Md. Mominul, Tsunoda, Masaru, Suzuki, Kaoru, Yamamoto, Tamotsu, Kawai, Gota, Kondo, Jiro, Takénaka, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2016
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933000/
https://ncbi.nlm.nih.gov/pubmed/27380367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16007767
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