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Profiling of integral membrane proteins and their post translational modifications using high-resolution mass spectrometry
Integral membrane proteins pose challenges to traditional proteomics approaches due to unique physicochemical properties including hydrophobic transmembrane domains that limit solubility in aqueous solvents. A well resolved intact protein molecular mass profile defines a protein’s native covalent st...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3498814/ https://ncbi.nlm.nih.gov/pubmed/21982782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2011.09.019 |
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