Protein-Sequence Polymorphisms and Post-translational Modifications in Proteins from Human Saliva using Top-Down Fourier-transform Ion Cyclotron Resonance Mass Spectrometry

Single nucleotide polymorphisms (SNPs) can result in protein sequence polymorphisms (PSPs) when codon translations are altered. Both top-down and bottom-up proteomics strategies can identify PSPs, but only if databases and software are used with this in mind. A 14319 Da protein from human saliva was...

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Bibliografiska uppgifter
Huvudupphovsmän: Whitelegge, Julian P., Zabrouskov, Vlad, Halgand, Frederic, Souda, Puneet, Bassilian, Sara, Yan, Weihong, Wolinsky, Larry, Loo, Joseph A., Wong, David T. W., Faull, Kym F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2131703/
https://ncbi.nlm.nih.gov/pubmed/19050733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2007.08.008
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