Post-translational Modifications of Integral Membrane Proteins Resolved by Top-down Fourier Transform Mass Spectrometry with Collisionally Activated Dissociation

Integral membrane proteins remain a challenge to proteomics because they contain domains with physicochemical properties poorly suited to today's bottom-up protocols. These transmembrane regions may potentially contain post-translational modifications of functional significance, and thus develo...

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Detalhes bibliográficos
Main Authors: Ryan, Christopher M., Souda, Puneet, Bassilian, Sara, Ujwal, Rachna, Zhang, Jun, Abramson, Jeff, Ping, Peipei, Durazo, Armando, Bowie, James U., Hasan, S. Saif, Baniulis, Danas, Cramer, William A., Faull, Kym F., Whitelegge, Julian P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
PTM Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871414/
https://ncbi.nlm.nih.gov/pubmed/20093275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900516-MCP200
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