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Post-translational Modifications of Integral Membrane Proteins Resolved by Top-down Fourier Transform Mass Spectrometry with Collisionally Activated Dissociation
Integral membrane proteins remain a challenge to proteomics because they contain domains with physicochemical properties poorly suited to today's bottom-up protocols. These transmembrane regions may potentially contain post-translational modifications of functional significance, and thus develo...
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Asıl Yazarlar: | , , , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
The American Society for Biochemistry and Molecular Biology
2010
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2871414/ https://ncbi.nlm.nih.gov/pubmed/20093275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900516-MCP200 |
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