Crystallization and preliminary X-ray diffraction analysis of tau protein microtubule-binding motifs in complex with Tau5 and DC25 antibody Fab fragments

Lignende værker

• Crystallization and preliminary X-ray diffraction analysis of two peptides from Alzheimer PHF in complex with the MN423 antibody Fab fragment
  af: Skrabana, Rostislav, et al.
  Udgivet: (2012)
• Identification of structural determinants on tau protein essential for its pathological function: novel therapeutic target for tau immunotherapy in Alzheimer’s disease
  af: Kontsekova, Eva, et al.
  Udgivet: (2014)
• Therapeutic antibody targeting microtubule-binding domain prevents neuronal internalization of extracellular tau via masking neuron surface proteoglycans
  af: Weisová, Petronela, et al.
  Udgivet: (2019)
• Humanized tau antibodies promote tau uptake by human microglia without any increase of inflammation
  af: Zilkova, Monika, et al.
  Udgivet: (2020)
• First-in-man tau vaccine targeting structural determinants essential for pathological tau–tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer’s disease model
  af: Kontsekova, Eva, et al.
  Udgivet: (2014)