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Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naïve CD4(+) and CD8(+) T cells
Naïve T cells continually recirculate between blood and secondary lymphoid organs, scanning dendritic cells (DC) for foreign antigen. Despite its importance for understanding how adaptive immune responses are efficiently initiated from rare precursors, a detailed quantitative analysis of this fundam...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497782/ https://ncbi.nlm.nih.gov/pubmed/23071319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211717109 |
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