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The race for the prize: T-cell trafficking strategies for optimal surveillance

The initiation of T-cell responses requires rare precursors to locate a draining lymph node (dLN) and encounter dendritic cells (DCs) presenting peptide-major histocompatibility complexes (pMHCs). To locate this needle in the haystack rapidly, T cells face an optimization problem—what is the most ef...

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Bibliografiske detaljer
Main Authors: Lee, Minyi, Mandl, Judith N., Germain, Ronald N., Yates, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423781/
https://ncbi.nlm.nih.gov/pubmed/22773385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-424655
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