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B-cell follicle development remodels the conduit system and allows soluble antigen delivery to follicular dendritic cells

Afferent lymph is transported throughout lymph nodes (LNs) by the conduit system. Whereas this conduit network is dense in the T-cell zone, it is sparse in B-cell follicles. In this study, we show that this differential organization emerges during lymph node development. Neonatal LNs lack B follicle...

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Detalhes bibliográficos
Main Authors: Bajénoff, Marc, Germain, Ronald N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788973/
https://ncbi.nlm.nih.gov/pubmed/19713459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-06-229567
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