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Link between intraphagosomal biotin and rapid phagosomal escape in Francisella

Cytosolic bacterial pathogens require extensive metabolic adaptations within the host to replicate intracellularly and cause disease. In phagocytic cells such as macrophages, these pathogens must respond rapidly to nutrient limitation within the harsh environment of the phagosome. Many cytosolic pat...

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Autores principales: Napier, Brooke A., Meyer, Lena, Bina, James E., Miller, Mark A., Sjöstedt, Anders, Weiss, David S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497780/
https://ncbi.nlm.nih.gov/pubmed/23071317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206411109
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