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A Francisella Virulence Factor Catalyzes an Essential Reaction of Biotin Synthesis

We recently identified a gene (FTN_0818) required for Francisella virulence that seemed likely involved in biotin metabolism. However, the molecular function of this virulence determinant was unclear. Here we show that this protein named BioJ is the enzyme of the biotin biosynthesis pathway that det...

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Detalhes bibliográficos
Main Authors: Feng, Youjun, Napier, Brooke A., Manandhar, Miglena, Henke, Sarah K, Weiss, David S., Cronan, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933004/
https://ncbi.nlm.nih.gov/pubmed/24313380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12460
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