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The Atypical Occurrence of Two Biotin Protein Ligases in Francisella novicida Is Due to Distinct Roles in Virulence and Biotin Metabolism

The physiological function of biotin requires biotin protein ligase activity in order to attach the coenzyme to its cognate proteins, which are enzymes involved in central metabolism. The model intracellular pathogen Francisella novicida is unusual in that it encodes two putative biotin protein liga...

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Pubblicato in:mBio
Autori principali: Feng, Youjun, Chin, Chui-Yoke, Chakravartty, Vandana, Gao, Rongsui, Crispell, Emily K., Weiss, David S., Cronan, John E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462617/
https://ncbi.nlm.nih.gov/pubmed/26060274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00591-15
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