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Counteracting chemical chaperone effects on the single-molecule α-synuclein structural landscape
Protein structure and function depend on a close interplay between intrinsic folding energy landscapes and the chemistry of the protein environment. Osmolytes are small-molecule compounds that can act as chemical chaperones by altering the environment in a cellular context. Despite their importance,...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497778/ https://ncbi.nlm.nih.gov/pubmed/22826265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201802109 |
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