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Counteracting chemical chaperone effects on the single-molecule α-synuclein structural landscape

Protein structure and function depend on a close interplay between intrinsic folding energy landscapes and the chemistry of the protein environment. Osmolytes are small-molecule compounds that can act as chemical chaperones by altering the environment in a cellular context. Despite their importance,...

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Bibliografski detalji
Glavni autori: Ferreon, Allan Chris M., Moosa, Mahdi Muhammad, Gambin, Yann, Deniz, Ashok A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497778/
https://ncbi.nlm.nih.gov/pubmed/22826265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201802109
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