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High-resolution temperature-concentration diagram of α-synuclein conformation obtained from a single Förster resonance energy transfer image in a microfluidic device
We present a microfluidic device for rapid and efficient determination of protein conformations in a range of medium conditions and temperatures. The device generates orthogonal gradients of concentration and temperature in an interrogation area that fits into the field of view of an objective lens...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846235/ https://ncbi.nlm.nih.gov/pubmed/19555081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac901008c |
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