Preparation and Physicochemical Properties of Vinblastine Microparticles by Supercritical Antisolvent Process

The objective of the study was to prepare vinblastine microparticles by supercritical antisolvent process using N-methyl-2-pyrrolidone as solvent and carbon dioxide as antisolvent and evaluate its physicochemical properties. The effects of four process variables, pressure, temperature, drug concentr...

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Autores principales: Zhang, Xiaonan, Zhao, Xiuhua, Zu, Yuangang, Chen, Xiaoqiang, Lu, Qi, Ma, Yuliang, Yang, Lei
Formato: Artigo
Lenguaje:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497290/
https://ncbi.nlm.nih.gov/pubmed/23202916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131012598
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