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Optimization of the preparation process of vinblastine sulfate (VBLS)-loaded folateconjugated bovine serum albumin (BSA) nanoparticles for tumor-targeted drug delivery using response surface methodology (RSM)

Response surface methodology (RSM) was used to optimize the process of preparing bovine serum albumin (BSA) nanoparticles by desolvation, then the resulting BSA nanoparticles (BSANPs) were conjugated with folate to produce a drug carrier system that can specifically target tumors. The anticancer dru...

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Autors principals: Zu, Yuangang, Zhang, Yu, Zhao, Xiuhua, Zhang, Qi, Liu, Yang, Jiang, Ru
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802044/
https://ncbi.nlm.nih.gov/pubmed/20054435
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