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Preparation and Physicochemical Properties of Vinblastine Microparticles by Supercritical Antisolvent Process
The objective of the study was to prepare vinblastine microparticles by supercritical antisolvent process using N-methyl-2-pyrrolidone as solvent and carbon dioxide as antisolvent and evaluate its physicochemical properties. The effects of four process variables, pressure, temperature, drug concentr...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Molecular Diversity Preservation International (MDPI)
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497290/ https://ncbi.nlm.nih.gov/pubmed/23202916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131012598 |
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